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Introduction to Simulation Studies: What They Are and Why They Matter

Insights | March 11, 2025

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Simulation studies are a unique approach for conducting an exposure assessment, allowing hazardous conditions to be created in the controlled setting of an exposure simulation testing chamber enabling real-world scenario testing.  Simulated exposure testing can be performed for a variety of chemical and particulate substances including dusts, fumes, gases, or vapors.

Why Simulation Studies Matter

The benefits of simulations studies include generating exposure data that can be integral in assessing workplace and community health risks without exposing unprotected populations.  An exposure simulation can be designed to study historical exposures for job sites that no longer exist, replicate current work practices for existing facilities and operations, or evaluate potential future exposure scenarios.  The information gained from a simulation study can also be a vital aspect in product research and development, helping to ensure that potential health exposures from a new product are understood and properly mitigated.  Simulation product testing can also provide valuable data for regulatory compliance including California Prop 65 and EPA test orders.

Types of Simulation Testing

In addition to conducting bench-scale and full-scale product exposure testing, C&IH’s simulation testing chamber can be utilized to perform a broad range of exposure assessments through replicating workplace contaminant scenarios.  Organizations across multiple industries have utilized simulation studies to better understand occupational health exposures specific to their operational processes and products or byproducts.  Examples of occupational health exposures that can be replicated and studied in an exposure simulation testing chamber include:

  • Nanoparticle exposure during semiconductor production
  • Silica dust exposure during sandblasting activities
  • Hydrocarbon vapor exposure during oil and gas pipeline repair
  • Lead exposure during demolition activities
  • Asbestos fiber exposure during gasket removal
  • VOC exposures from chemical by-products and off-gassing under in-use conditions

Exposure Simulation Design

The design of C&IH’s exposure simulation testing facility includes modifiable walls, ceilings, and surface materials, as well as adjustable air flow rates into and out of the chamber.  The facility’s modular and adjustable design allows real-world parameters to be incorporated into an exposure simulation, enabling study outcomes to better characterize specific and unique exposure scenarios.

C&IH’s simulation testing facility is designed to help organizations perform an in-depth study of real-time contaminant dispersion associated with industry-specific work practices and product exposures.  Our team of scientists can assist your organization with the creation of study designs that meet regulatory requirements and help manage health risks impacting the workforce and community.

Contact us to discuss the unique needs of your exposure simulation and how our team can help.

C&IH provides national and international consulting from our office located near Denver, Colorado.

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7333 W. Jefferson Ave., Suite 235

Lakewood, CO 80235

(303) 420-8242

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